Multifunctional microsphere formulation of fluorescent magnetic properties for drug delivery system

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Kusrini, Eny and Prassanti, Riesna and Nurjaya, Dwi Marta and Gunawan, Cindy (2017) Multifunctional microsphere formulation of fluorescent magnetic properties for drug delivery system. In: The First International Symposium of Biomedical Engineering (ISBE 2016), 31 May–1 June 2016, Depok City, Indonesia.

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abs/10.1063/1.4976780 - Published Version
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Official URL: http://doi.org/10.1063/1.4976780

Abstract

The microsphere formulations of Chit/TPP/Sm/Fe3O4/Rn were prepared by an ionic gelation technique, where
Chit = chitosan, TPP = tripolyphosphate, Sm = samarium and Rn = ranitidine. Optimum of microsphere formulation exhibit magnetic and fluorescent properties with adsorption efficiency of ~92% was obtained for Chit/TPP/Sm/Fe3O4/Rn with ratio 400:500:50:1:20. Fluorescence intensity of microsphere formulations increased with the cumulative amount release of ranitidine, so that the changing of fluorescence intensity at wavelength of 590 nm referring to the Sm3+ ion could be used as indicator in DDS. With the demonstration of sustained release from microsphere formulation, it allows to investigate the applications to other drugs.

Item Type:	Conference or Workshop Item (Paper)
Subjects:	Taksonomi BATAN > Daur Bahan Bakar Nuklir dan Bahan Maju > Bahan Galian Nuklir > Teknik Pengolahan Bahan Galian Nuklir Taksonomi BATAN > Daur Bahan Bakar Nuklir dan Bahan Maju > Bahan Galian Nuklir > Teknik Pengolahan Bahan Galian Nuklir
Divisions:	BATAN > Pusat Teknologi Bahan Galian Nuklir IPTEK > BATAN > Pusat Teknologi Bahan Galian Nuklir
Depositing User:	Administrator Repository
Date Deposited:	04 May 2018 09:58
Last Modified:	31 May 2022 04:35
URI:	https://karya.brin.go.id/id/eprint/943

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