Sunaryanto, Rofiq and Marwoto, Bambang and Irawadi, Tun Tedja and Mas'ud, Zainal Alim (2010) Antibiotic compound from marine actinomycetes (Streptomyces sp a11): isolation and structure elucidation. Indonesian Journal of Chemistry, 10 (2). pp. 226-232.
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Abstract
Purification and structure elucidation of antibiotic produced by marine actinomycetes (Streptomyces sp A11)
was conducted. Production of antibiotic was carried out by liquid fermentation using yeast and peptone medium for 5
days fermentation. Purification of antibiotic was carried out by silica gel 60 (Merck, 0.063-0.200 mm) column
chromatography and preparative HPLC. Structure elucidation was carried out using ESI-MS, 1H NMR, 13C NMR,
DEPT 13C NMR, and FTIR. This antibiotic was identified as cyclo (tyrosyl-prolyl) / (C14H16N2O3). This antibiotic had
biological activity to Escherichia coli ATCC 25922, Staphylococcus aureus ATCC25923, Bacillus subtilis ATCC
66923, Pseudomonas aeruginosa ATCC27853, and produced by extracellular secretion.
| Item Type: | Article |
|---|---|
| Additional Information: | DDC'23: 577.6 |
| Uncontrolled Keywords: | Antibiotic; Actinomycetes; Purification,; Structure elucidation |
| Subjects: | Ocean Sciences & Technology > Marine Geophysics & Geology Medicine & Biology > Ecology |
| Depositing User: | Rasty - |
| Date Deposited: | 10 Oct 2022 04:34 |
| Last Modified: | 10 Oct 2022 04:34 |
| URI: | https://karya.brin.go.id/id/eprint/12216 |
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