Alliaceumolide A: A rare undescribed 17-membered macrolide from Indonesian Dysoxylum alliaceum

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Riyadi, Sandra Amalia and Naini, Al Arofatus and Mayanti, Tri and Farabi, Kindi and Harneti, Desi and Nurlelasari, Nurlelasari and Maharani, Rani and Lesmana, Ronny and Fajriah, Sofa and Jungsuttiwong, Siriporn and Awang, Khalijah and Azmi, Mohamad Nurul and Supratman, Unang (2024) Alliaceumolide A: A rare undescribed 17-membered macrolide from Indonesian Dysoxylum alliaceum. Phytochemistry Letters, 62. pp. 73-77. ISSN 18743900

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Official URL: https://doi.org/10.1016/j.phytol.2024.07.004

Abstract

Alliaceumolide A (1), a new macrolide together with known ivorenolide B (2) were isolated from Dysoxylum alliaceum (Blume) Blume ex A.Juss. These compounds were classified as 17-membered macrolide, which is a rare structure for plant-derived natural products. The structures were elucidated by extensive spectroscopic analyses, and the absolute configuration of 1 was determined by electronic circular dichroism (ECD) using TDDFT method. Furthermore, compounds 1 and 2 were tested for cytotoxic activity against two cancer MCF-7 and HeLa cell lines.

Item Type:	Article
Subjects:	Chemistry
Depositing User:	Maria Regina
Date Deposited:	12 Dec 2025 17:39
Last Modified:	12 Dec 2025 17:39
URI:	https://karya.brin.go.id/id/eprint/56217

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