Clinical manifestations of the gastrointestinal system in patients with SARS-CoV-2 infection

Kharizmatika, Kharizmatika and Judya, Sukmana and Roostantia, Indrawati and Christian, Bambang Sulistio (2024) Clinical manifestations of the gastrointestinal system in patients with SARS-CoV-2 infection. MAHESA: Malahayati Health Student Journal, 4 (10): 33. pp. 4582-4597. ISSN 2746-198X

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Abstract

SARS-CoV-2 infection was declared as a pandemic by the WHO since March 11, 2020, with confirmed cases increasing every year. SARS-CoV-2 is one of the varian of coronavirus that has a higher transmission rate, where it is transmitted through infected droplets. SARS-CoV-2 can manifest in the digestive tract. This descriptive study uses a literature study method. Diarrhea was a common symptom of gastrointestinal manifestations in Covid-19 patients. Apart from diarrhea, other symptoms are anorexia, nausea, vomiting and abdominal pain. Gender prevalence varies. The average age of patients exposed to COVID-19 was over 50 years with hypertension as the most common comorbidity. SARS-CoV-2 are associated with Gastrointestinal manifestations which binds to ACE2 on gastrointestinal epithelial cells. SARS-CoV-2 infection causes an imbalance in the gut microbiota that can trigger secondary infections and multiple organ disorders and affect the severity of Covid-19.

Item Type: Article
Uncontrolled Keywords: Gastrointestinal symptoms, ACE2, Gut microbiota, Gut-lung axis, SARS-CoV-2, Digestive system diseases, Covid-19
Subjects: Medicine & Biology > Immunology
Medicine & Biology > Microbiology
Depositing User: Djaenudin djae Mohamad
Date Deposited: 21 Oct 2024 13:47
Last Modified: 21 Oct 2024 13:47
URI: https://karya.brin.go.id/id/eprint/50753

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