Comparison of immunoglobulin M immunoglobulin G antibody detection and severe acute respiratory syndrome Corona virus 2 antigen detection

COVID-19 disease is a disease caused by infection with SARS-CoV-2. COVID-19 is currently a disease that attacks not only in one country but also attacks all countries in the world. Various methods have been used by governments in all countries to detect and treat this disease. The rapid test for IgM and IgG antibodies using the principle of immunochromatography is considered easier to do than other tests and can be used as an initial suspicion of SARSCoV-2 infection. Recently, the rapid test for SARS-CoV-2 antigen has also developed. This study aims to compare the detection of IgM and IgG anti-SARS-CoV-2 antibodies and the detection of SARS-CoV-2 antigen in patients at hospitals in North Sulawesi. The specific target is to obtain data on the detection of anti-SARS-CoV-2 IgM and IgG antibodies and the detection of SARS-CoV-2 antigen in patients in hospitals. The type of research used was descriptive research with a cross-sectional research design which was carried out at Budi Mulia Bitung Hospital and Boroko Bolmut Hospital. The data collection technique, namely antibody detection, was carried out by dripping the patient's serum on the antibody detection-based rapid diagnostic test kit and nasal swabs on the antigen detection-based rapid diagnostic test kit and interpreted according to the results obtained. The results of antigen detection examination in 232 patients if categorized by sex, males showed more reactive results, namely 7 patients (3%), while females were 6 patients (2.6%) of all patients examined. SARS Cov- 2. The results of antibody detection examinations in 50 patients if categorized by gender, women showed more reactive results, namely 7 patients, which was 14% of the total examined for anti-SARS Cov-2 antibodies. The results of this study are expected to provide input to related government agencies and to increase government awareness of the spread of COVID-19 in the community.