Abstract
Technetium-99m (99mTc), the daughter radionuclide of Molybdenum-99 (99Mo), is the most widely used radionuclide in the world and predicted to face a shortage in the future. A Zirconium-based material(ZBM) is an alternative solution to overcome this problem due to its high adsorption capacity toward 99Mo, and ability to release 99mTc. The performance of the ZBM is influenced by its material properties, especially the surface area and pore diameter. This study aims to characterize and evaluate the ZBM developed by new synthesis method. The ZBM was synthesized using zirconium(IV) chloride, 2-propanol, water and tetrahydrofuran. The drying process after synthesis was conducted by gradual heating. The resulting material was analysed by XRD, SEM, and BET method. The 99Mo adsorption and 99mTc releasing capacity was also evaluated. The analysis result shows that the ZBM is an amorphous material, while its surface area, pore volume, and pore diameter was 45.8 m2/g, 0.19 cm3/g, and 16.29 nm, respectively. The 99Mo adsorption, and 99mTc releasing capacity of the ZBM was 181.58 mg Mo/g ZBM, and 91.81%, respectively.
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References
- [1]Ahmad M. 2011 Ann. Nucl. Med. 25 677
- [2]Jürgens S., Herrmann W. A. and Kühn F. E. 2014 J. Organomet. Chem. 751 83
- [3]Welsh J., Bigles C. I. and Valderrabano A. 2015 J. Radioanal. Nucl. Chem. 305 9
- [4]Guedes-Silva C. C., Ferreira T. S., Carvalho F. M. S., Paula C. M. and Otubo L. 2016 Mater. Res. 19 791
- [5]Ruth T. J. 2014 J. Nucl. Med. Technol. 42 245
- [6]Nakai B. K., Takahashi N., Hatazawa J., Hinohara A. S., Hayashi Y., Ikeda H., Kanai Y., Watabe T., Fukuda M. and Hatanaka K. 2014 Proc. Jpn. Acad. Scr. 90 413
- [7]Selivanova S. V., Lavallée E., Senta H., Caouette L., McEwan A. J. B., Guérin B., Lecomte R. and Turcotte E. 2017 J. Nucl. Med. 58 791
- [8]Hou X., Tanguay J., Buckley K., Schaffer P., Bénard F., Ruth T. J. and Celler A. 2016 Phys. Med. Biol. 61 542
- [9]Blaauw M., Ridikas D., Baytelesov S. et al 2017 J. Radioanal. Nucl. Chem. 311 409
- [10]Kambali I. 2017 Makara J. Sci. 21 125
- [11]Kambali I., Suryanto H., Parwanto P., Rajiman R. and Marlina M. 2016 Proc. Cyclotrons 83
- [12]Hudait A. K., Pal A. K., Saha S. D., Chattopadhyay S., Banerjee S., Alam M. N., Kumar U., Barua L. and Madhusmita 2018 Appl. Radiat. Isot. 143 41
- [13]Sekimoto S., Tatenuma K., Suzuki Y., Tsuguchi A., Tanaka A., Tadokoro T., Kani Y., Morikawa Y., Yamamoto A. and Ohtsuki T. 2017 J. Radioanal. Nucl. Chem. 311 1361
- [14]Gumiela M., Dudek J. and Bilewicz A. 2016 J. Radioanal. Nucl. Chem. 310 1061
- [15]Pillai M. R. A, Dash A. and Knapp F. F. 2015 J. Nucl. Med. 56 159
- [16]Marlina M., Sarmini E., Herlina H., Sriyono S., Saptiama I., Setiawan H. and Kadarisman 2017 Atom Indones. 43 1
- [17]Saptiama I., Kaneti Y. V., Yuliarto B., Kumada H. et al 2019 Chem. Eur. J. 25 4843
- [18]Awaludin R., Gunawan A., Lubis H., Sriyono, Herlina, Mutalib A., Kimura A., Tsuchiya K., Tanase M. and Ishihara M. 2015 J. Radioanal. Nucl. Chem. 303 1481
- [19]Saptiama I., Lestari E., Sarmini E., Lubis H., Marlina M. and Mutalib A. 2016 Atom Indones. 42 115
- [20]Saptiama I., Marlina M., Sarmini E., Herlina, Sriyono, Abidin A., Setiawan H., Kadarisman, Lubis H. and Mutalib A. 2015 Atom Indones. 41 103
- [21]Le V., Do Z., Le M., Le V. and Le N. 2014 Molecules 19
- [22]Chakravarty R. and Dash A. 2013 J. Nanosci. Nanotechnol. 13 2431
- [23]Chakravarty R., Ram R. and Dash A. 2014 Sep. Sci. Technol. 49 1825
- [24]Saptiama I., Kaneti Y. V., Oveisi H. et al 2018 Bull. Chem. Soc. Jpn. 91 195
- [25]Saptiama I., Kaneti Y. V., Suzuki Y. et al 2017 Bull. Chem. Soc. Jpn. 90 1174
- [26]Saptiama I., Kaneti Y. V., Suzuki Y., Tsuchiya K., Fukumitsu N., Sakae T., Kim J., Kang Y-M., Ariga K. and Yamauchi Y. 2018 Small 14 1800474
- [27]Munir M., Sarmini E., Herlina, Pujiyanto A., Saptiama I., Kadarisman and Kurnia S. 2018 J. Kim. Kemasan 40 87