Abstract
It has been conducted the synthesize of single phase of hydroxyapatite (HAp) from ale-ale (Meretrix meretrix) clamshell waste by using double-stirring precipitation method. The biocompatibility of HAp-coated CoCrMo alloy was examined as a coating material of implant. The coating of CoCrMo alloy which was treated by using electrophoretic deposition method showed that the surface morphology was well-densified and crack-free. Corrosion resistance test showed the corrosion rate at the level of 0.0055 mils per year (mpy) on HAp-coated CoCrMo alloy, this result was better than that of uncoated CoCrMo alloy (0.0224 mpy). In vitro cytocompatibility assay in endothelial cell of Calf Pulmonary Artery Endothelium (CPAE) (ATCC-CCL 209) showed that there was no toxicity in cell culture with the percent inhibition of 33.33% after 72 hours of coated CoCrMo alloy incubation. Based on this corrosion resistance and cytocompatibility properties, HAp-coated CoCrMo alloy has the potency for bone implant application.
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